Hypoxic ischemic encephalopathy HIE is a significant cause of mortality and short- and long-term morbidities. This study aims to determine the incidence of HIE in our country, to assess the TH management in infants with HIE, and present short-term outcomes of these infants. The rates of mild, moderate and severe HİE were TH was administered to 85 The incidence of HIE remained similar over time with a reduction in mortality rate. Longer follow-up studies are necessary for this vulnerable population. Copyright: © Okulu et al. This is an open access article distributed under the terms of the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability: All relevant data are within the paper and its Supporting Information files. Competing interests: The authors have declared that no competing interests exist. Hypoxic ischemic encephalopathy HIE is a major cause of mortality and short- and long-term morbidities. In a recent study from New Zealand, NE was found to have an incidence of 1. However, there were significant differences in reported incidences between population-based and hospital-based research. According to the data published by Bangladeshi Sex Offenders Lawyer Hypoxic Ischemic Encephalopathy Study Group of the Turkish Neonatology Society in Türkiye in93 infants out of 19, live births were diagnosed with HIE, resulting in a frequency of 2. However, a recent study evaluating the use of TH for HIE in low-income countries found it to be neither effective nor safe, and advises against its use [ 10 ], in which these results and conclusions should be carefully considered. There is not enough evidence to determine any significant benefits or Bangladeshi Sex Offenders Lawyer from using TH in infants with mild HIE [ 1112 ]. This study aimed to determine the incidence of HIE in Türkiye, assess TH management in infants with HIE, and present short-term outcomes of these infants, including the underlying etiologies, clinical features, morbidity and mortality. This was a multicenter, prospective, observational, nationally-based cohort study conducted between 15 March, and 15 April All participating centers all had an attending neonatologists and almost all included a pediatric neurologists. For multiorgan dysfunction, the following conditions were considered [ 14 — 16 ]:. The number of moderate or severe signs determined the degree of encephalopathy; if signs were distributed equally, then the designation was based on the level of consciousness [ 1718 ]. To determine the incidence of HIE, the number of infants admitted to the participating units during the study period, whether the cases included in the study group were born inborn or outborn, and the number of deliveries performed in the same center during the study period was asked from the participating centers. Data for each neonate was recorded, including GA, birth weight BWsex, place of birth, APGAR scores at 5-,and min, mode of delivery, delivery room resuscitation, underlying etiologies, Thompson scores at admission and during the first 72 h after birth [ 19 ], and whether cooling therapy was given. Care practices, such as amplitude electroencephalography aEEG at admission, timing of nactive TH initiation with servo-controlled device after birth in hthe duration of TH, need for respiratory support, accompanying organ systems issues aside from CNS condition, the results of MRI, EEG, and hearing screening test, and mortality rate were all recorded. Mortality was defined as mortality before NICU discharge. The aEEG background activity was classified as follows [ 20 ]:. Only de-identified data were provided to the registry, negating the need for informed consent. The local institutional review board reviewed and approved registry participation with the approval No. Categorical variables were reported as number and percentage, and continuous variables as mean ± SD or median IQR where appropriate. We used the Student-t test to analyze continuous variables with a normal distribution, and the Mann-Whitney U test for non-normally distributed data. We used the post hoc Bonferroni test to analyze the differences between each group. Logistic regression was applied Bangladeshi Sex Offenders Lawyer calculate the odss ratio to access association between risk and covariates. All statistical analyses were performed using SPSS version Participating hospitals recorded births during the study period, and a total of infants were admitted for neonatal care. Among them, The incidence for mild HIE was 0. Of the total infants, The mean GA and BW for these infants were The mean maternal age was Most of the infants received resuscitation in the delivery room The clinical and laboratory findings, as well as short-term outcomes for infants are presented in Table 2. The most frequent problems were respiratory problems, inotrope required hypotension and electrolyte imbalances.
Ristock, Janice. Eş anlamlılar sözlüğü. Çevirmen aracı. University of Pennsylvania Law Review. Metropolitan Police UK.
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